反应条件
1: 87.5 percent / isopropylcyclohexylamine, n-butyllithium, methylmagnesium bromide / toluene; hexane; diethyl ether / 24 h / 0 °C
2: 61 percent / triethylamine / CH2Cl2 / -78 °C
3: 1.) 2,6-lutidine, trifluoroacetic anhydride, 2.) mercuric chloride (aq.) / 1.) acetonitrile, -40 deg C, 1 h, 2.) 25 deg C, 2 h
View Scheme
参考文献
Tius, Marcus A.; Kerr, Michael A.
Synthetic Communications, 1988 , vol. 18, # 16-17 p. 1905 - 1912
