4-甲基-1,3-二氢咪唑-2-酮合成路线 （共 17 条）
反应条件
hydrogenchloride; sodium hydrogencarbonate; sodium carbonate in methanol; ethanol; chloroform
参考文献
Merrell Dow Pharmaceuticals Inc.
Patent: US5338862 A1, 1994 ;
反应条件
hydrogenchloride; palladium on activated charcoal P=36775.4 Torr; Erwaermen des Reaktionsgemisches mit Kaliumcyanat;
参考文献
Chemische Berichte, , vol. 96, p. 381 - 384
Journal of the American Chemical Society, , vol. 67, p. 2079,2082
参考文献
Journal of the American Chemical Society, , vol. 67, p. 2079,2082
参考文献
Glass; Buschauer; Tenor; Bartel; Will-Shahab; Krause
Archiv der Pharmazie, 1995 , vol. 328, # 10 p. 709 - 719
反应条件
ammonium hydroxide 4 h; Heating;
参考文献
Shvaika, O. P.; Korotkikh, N. I.; Chervinskii, A. Yu.; Artemov, V. N.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 8 p. 1533 - 1543
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 8 p. 1728 - 1739
反应条件
thionyl chloride; aluminium trichloride in nitrobenzene; benzene
参考文献
MYOGEN, INC.; AVENTIS PHARMACEUTICAL, INC.
Patent: WO2005/58280 A2, 2005 ;
Location in patent: Page/Page column 19 ;
反应条件
aluminium trichloride in nitrobenzene T=60 - 65°C; 6 h;
参考文献
Schnettler; Dage; Grisar
Journal of Medicinal Chemistry, 1982 , vol. 25, # 12 p. 1477 - 1481
反应条件
aluminium trichloride in nitrobenzene
T=60°C; 6 h;
参考文献
Glass; Buschauer; Tenor; Bartel; Will-Shahab; Krause
Archiv der Pharmazie, 1995 , vol. 328, # 10 p. 709 - 719
反应条件
aluminium trichloride in nitrobenzene
T=60°C; 6 h;
参考文献
Glass; Buschauer; Tenor; Bartel; Will-Shahab; Krause
Archiv der Pharmazie, 1995 , vol. 328, # 10 p. 709 - 719
反应条件
aluminium trichloride in nitrobenzene
Acylation;
参考文献
El-Moselhy, Tarek F.; El-Kersh, Mohamed A.; Nyberg, Fred; Hede, Ragnar; Eldawy, Mohamed A.
Medicinal Chemistry Research, 1998 , vol. 8, # 3 p. 163 - 170
