5-吡啶-2-基噻吩-2-乙酸合成路线 （共 5 条）
反应条件
1: 76.8 percent / cobaltocene / tetrahydrofuran / 4 h / 140 °C / 9120 Torr 2: 1.) 1.5 N BuLi/hexane / 1.) THF, 0 deg C, 15 min, 2.) -78 deg C View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 25, # 3.2 p. 570 - 575
Zhurnal Organicheskoi Khimii, , vol. 25, # 3 p. 633 - 639
反应条件
1: 67 percent / Br2, glacial acetic acid / 6 h 2: 1.) BuLi / 1.) -78 deg C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 1 p. 201 - 219
反应条件
n-butyllithium; hexane 1.) THF, 0 deg C, 15 min, 2.) -78 deg C; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 25, # 3.2 p. 570 - 575
Zhurnal Organicheskoi Khimii, , vol. 25, # 3 p. 633 - 639
反应条件
n-butyllithium 1.) -78 deg C; Yield given. Multistep reaction;
参考文献
Journal of Chemical Research, Miniprint, , # 1 p. 201 - 219
反应条件
thionyl chloride in toluene
参考文献
American Cyanamid Company
Patent: US5654297 A1, 1997 ;
US 5654297 A
