3,4,5-三甲氧基苯甲酸合成路线 （共 210 条）
参考文献
Perkin; Weizmann
Journal of the Chemical Society, 1906 , vol. 89, p. 1655
参考文献
v. Kostanecki; Tambor
Chemische Berichte, 1906 , vol. 39, p. 4023
参考文献
Graebe; Suter
Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 230
反应条件
1: water containing CHCl3; bromine 2: copper-powder; aqueous NH3 3: diazomethane; diethyl ether View Scheme
参考文献
Zhang, Zhichao; Liang, Xiaomeng; Li, Xiangqian; Song, Ting; Chen, Qingbin; Sheng, Hongkun
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 711 - 718
反应条件
1: HCl 2: LiAlH4 / tetrahydrofuran 3: H2 / Pd-C / acetic acid / 2206.5 Torr / Ambient temperature 4: aq. H2O2, AcOH, H2SO4 View Scheme
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
1: HCl 2: LiAlH4 / tetrahydrofuran 3: H2 / Pd-C / acetic acid / 2206.5 Torr / Ambient temperature 4: aq. H2O2, AcOH View Scheme
参考文献
Sugihara,H. et al.
Justus Liebigs Annalen der Chemie, 1972 , vol. 763, p. 109 - 120
反应条件
1.1: oxalyl chloride / N,N-dimethylformamide / CH2Cl2 2.1: Na 2.2: 83 percent / methanol / 5 h / 20 °C 3.1: 75 percent / hydrazine hydrate / ethanol / 24 h / Heating View Scheme
参考文献
Tavares; Penna; Amaral
Bollettino Chimico Farmaceutico, 1997 , vol. 136, # 3 p. 244 - 249
反应条件
1: fuming sulfuric acid / 33 - 40 °C 2: NaOH-solution View Scheme
参考文献
Bogert; Ehrlich
Journal of the American Chemical Society, 1919 , vol. 41, p. 806
反应条件
1: sulfuric acid / 40 - 50 °C 2: NaOH-solution 3: benzene; phosphorus pentachloride / 0 °C View Scheme
参考文献
Bradley; Robinson
Journal of the Chemical Society, 1928 , p. 1551
反应条件
sodium; tert-butyl alcohol 3.5 h; Heating;
参考文献
Sharda, Rekha; Krishnamurty, H. G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 5 p. 405 - 406
