N-羟甲基邻苯二甲酰亚胺合成路线 （共 74 条）
反应条件
sodium methylate in N,N-dimethyl-formamide
T=-25 - -20°C; 52 h;
参考文献
Cul, Armelle; Chihab-Eddine, Abderrahim; Pesquet, Anthony; Marchalin, Stefan; Daich, Adam
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 3 p. 499 - 505
反应条件
1: 87 percent / DBU / CH2Cl2 / 2 h / 20 °C
2: 87 percent / TMSOTf / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Ali, Ibrahim A. I.; Abdel-Rahman, Adel A.-H.; El Ashry, El Sayed H.; Schmidt, Richard R.
Synthesis, 2003 , # 7 p. 1065 - 1070
反应条件
1: phenyl-acetic acid methyl ester With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran
T=-78°C; 1 h;
2: 2-(hydroxymethyl)-1,3-isoindolinedione in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
trifluorormethanesulfonic acid; trifluoroacetic acid
Ambient temperature;
参考文献
Gong, Young-Dae; Iwasawa, Nobuharu
Chemistry Letters, 1994 , # 11 p. 2139 - 2142
