N-羟甲基邻苯二甲酰亚胺合成路线 （共 74 条）
参考文献
Carnegie Mellon University
Patent: US2003/224391 A1, 2003 ;
Location in patent: Page 11 ;
参考文献
Hellmann et al.
Justus Liebigs Annalen der Chemie, 1959 , vol. 626, p. 35,45
反应条件
N-methyl-pyrrolidine; sulfuric acid; lithium bromide; [PdBr2(PPh3)2] T=120°C; P=45003.6 Torr; 12 h;
参考文献
Enzmann, Armin; Eckert, Markus; Ponikwar, Walter; Polborn, Kurt; Schneiderbauer, Stefan; Beller, Matthias; Beck, Wolfgang
European Journal of Inorganic Chemistry, 2004 , # 6 p. 1330 - 1340
反应条件
sulfuric acid man kocht das hierbei entstandene N-<4-Nitro-3-methyl-benzyl>-phthalimid mit Wasser;
参考文献
Tscherniac
Patent: DE134979 ;
反应条件
nitric acid; acetic anhydride; urea in dichloromethane T=0 - 20°C; 24 h; Inert atmosphere;
参考文献
Dos Santos, Jean Leandro; Lanaro, Carolina; Lima, Ldia Moreira; Gambero, Sheley; Franco-Penteado, Carla Fernanda; Alexandre-Moreira, Magna Suzana; Wade, Marlene; Yerigenahally, Shobha; Kutlar, Abdullah; Meiler, Steffen E.; Costa, Fernando Ferreira; Chung, Manchin
Journal of Medicinal Chemistry, 2011 , vol. 54, # 16 p. 5811 - 5819
反应条件
1.1: thionyl chloride / 4 h / 75 °C / Inert atmosphere 2.1: sodium iodide / acetone / 4 h / 20 °C / Darkness 3.1: copper(l) iodide; diethylzinc / hexane; dichloromethane / 2 h / 20 °C / Inert atmosphere 3.2: 4 h / 20 °C / Inert atmosphere View Scheme
参考文献
Maury, Julien; Mouysset, Dominique; Feray, Laurence; Marque, Sylvain R. A.; Siri, Didier; Bertrand, Michele P.
Chemistry - A European Journal, 2012 , vol. 18, # 11 p. 3241 - 3247
反应条件
methanol; formaldehyd; water T=220°C;
参考文献
DE523693 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 18, p. 342
反应条件
1: thionyl chloride / 4 h / 75 °C / Inert atmosphere 2: sodium iodide / acetone / 4 h / 20 °C / Darkness 3: diethylzinc / hexane; dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 11 p. 3241 - 3247
反应条件
1: cesium fluoride, 18-crown-6, methanesulfonyl fluoride / tetrahydrofuran 2: cesium fluoride / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Pucher; Johnson
Journal of the American Chemical Society, 1922 , vol. 44, p. 823
反应条件
sodium methylate in N,N-dimethyl-formamide T=20°C; 6 h;
参考文献
Cul, Armelle; Chihab-Eddine, Abderrahim; Pesquet, Anthony; Marchalin, Stefan; Daich, Adam
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 3 p. 499 - 505
