1: dichloromethane / 48 h / 22 °C 2: triethylamine / dichloromethane / 1 h / 22 °C 3: dichloromethane / 24 h / Reflux 4: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16.5 h / 22 - 120 °C / Inert atmosphere 5: hydrogenchloride; water / N,N-dimethyl-formamide / 22 °C 6: sodium tetrahydroborate / methanol; dichloromethane / 0 - 22 °C View Scheme

1: triethylamine / dichloromethane / 1 h / 22 °C 2: dichloromethane / 24 h / Reflux 3: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16.5 h / 22 - 120 °C / Inert atmosphere 4: hydrogenchloride; water / N,N-dimethyl-formamide / 22 °C 5: sodium tetrahydroborate / methanol; dichloromethane / 0 - 22 °C View Scheme

1: palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene]; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16.5 h / 22 - 120 °C / Inert atmosphere 2: hydrogenchloride; water / N,N-dimethyl-formamide / 22 °C 3: sodium tetrahydroborate / methanol; dichloromethane / 0 - 22 °C View Scheme

1: triethylamine / dichloromethane / 0 - 22 °C 2: triethylamine / Reflux View Scheme

1: 9-(1-hydroxyethyl)-7-methyl-2-morpholin-4-yl-4H-pyrido[1,2-a]pyrimidin-4-one With phosphorus tribromide in dichloromethane T=40°C; 2.5 h; 2: anthranilic acid With triethylamine in dichloromethane T=40°C; 3: With hydrogenchloride; water in acetone T=20°C;