ammonia in methanol 16 h; Ambient temperature;

1: 58 percent / aq. HCl / 18 h / Heating 2: 60 percent / dimethylformamide / Ambient temperature; overnight 3: t-BuOK / dimethylformamide / 5 h / 80 °C 4: NH3 / methanol / 16 h / Ambient temperature View Scheme

1: 60 percent / dimethylformamide / Ambient temperature; overnight 2: t-BuOK / dimethylformamide / 5 h / 80 °C 3: NH3 / methanol / 16 h / Ambient temperature View Scheme

1: t-BuOK / dimethylformamide / 5 h / 80 °C 2: NH3 / methanol / 16 h / Ambient temperature View Scheme

1: 48 percent / K2CO3 / dimethylsulfoxide / 18 h / Ambient temperature 2: 58 percent / aq. HCl / 18 h / Heating 3: 60 percent / dimethylformamide / Ambient temperature; overnight 4: t-BuOK / dimethylformamide / 5 h / 80 °C 5: NH3 / methanol / 16 h / Ambient temperature View Scheme