N-(苄氧羰基)-L-丙氨酸对硝基苯酯合成路线 (共 15 条)
反应条件
n-ethyl morpholine; hexamethylphosphorous triamide dichloride in dichloromethane 1) 0 deg C, 2 h, 2) overnight, r.t.;
参考文献
Appel, Rolf; Glaesel, Ursula
Chemische Berichte, 1980 , vol. 113, # 11 p. 3511 - 3516
参考文献
Goodman; Stueben
Journal of the American Chemical Society, 1959 , vol. 81, p. 3980,3982
反应条件
1: 81 percent / Et3N / acetonitrile / 1 h / 5 °C 2: 70 percent / Et3N / H2O / 4 h / Ambient temperature; pH=10.0 View Scheme
参考文献
Kouge; Koizumi; Okai; Kato
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 7 p. 2409 - 2418
反应条件
1: quinoline 2: (i), (ii) DCC View Scheme
参考文献
Wolman,Y. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 689 - 690
反应条件
(i), (ii) DCC; Multistep reaction;
参考文献
Wolman,Y. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 689 - 690
反应条件
triethylamine in chloroform Ambient temperature;
参考文献
Arena, Giuseppe; Impellizzeri, Giuseppe; Maccarrone, Giuseppe; Pappalardo, Giuseppe; Sciotto, Domenico; Rizzarelli, Enrico
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 3 p. 371 - 376
反应条件
sodium hydroxide in water; butan-1-ol Ambient temperature;
参考文献
Litvinenko, L. M.; Kosmynin, V. V.; Kaida, L. N.; Savelova, V. A.; Verbovaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 4 p. 784 - 785
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 4 p. 877 - 878
反应条件
sodium hydroxide in water; butan-1-ol Ambient temperature;
参考文献
Litvinenko, L. M.; Kosmynin, V. V.; Kaida, L. N.; Savelova, V. A.; Verbovaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 4 p. 784 - 785
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 4 p. 877 - 878
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide; N-acetyl-L-His in water T=25°C; variation of pH, catalyst and their concentration, with an without anionic and non-ionic surfactants; Rate constantEquilibrium constant;
参考文献
Ihara, Yasuji; Hosako, Reiko; Nango, Mamoru; Kuroki, Nobuhiko
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 5 - 10
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide; Dec-L-His in acetonitrile T=25°C; 0.02M phosphate buffer, pH=7.3; other catalysts; Rate constant;
参考文献
Ohkubo, Katsutoshi; Funakoshi, Yoshio; Urata, Yasuo; Hirota, Shogo; Usui, Satoshi; Sagawa, Takashi
Journal of the Chemical Society, Chemical Communications, 1995 , # 20 p. 2143 - 2144