N-芴甲氧羰基-O-beta-(2-乙酰氨基-2-脱氧-3,4,6-三-O-乙酰基-alpha-D-吡喃半乳糖基)-L-苏氨酸合成路线 （共 41 条）
反应条件
hydrogen; palladium on activated charcoal in methanol; water P=760 Torr; 90 h;
参考文献
Kuduk, Scott D.
Journal of the American Chemical Society, 1998 , vol. 120, # 48 p. 12474 - 12485
反应条件
tetrakis(triphenylphosphine) palladium(0); N-methylaniline in tetrahydrofuran 1 h; Ambient temperature;
参考文献
Vuljanic, Tatjana; Bergquist, Karl-Erik; Clausen, Henrik; Roy, Sarbani; Kihlberg, Jan
Tetrahedron, 1996 , vol. 52, # 23 p. 7983 - 8000
反应条件
trifluoroacetic acid in methoxybenzene
参考文献
Brocke, Constanze; Kunz, Horst
Synlett, 2003 , # 13 p. 2052 - 2056
反应条件
1: 1.) AgClO4, 4A molecular sieves / 1.) CH2Cl2, RT, 10 min, 2.) CH2Cl2, RT, overnight 2: 76 percent / pyridine / 20 h / Ambient temperature 3: 92 percent / H2 / 5percent Pd/C / methanol; H2O / 90 h / 760 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 48 p. 12474 - 12485
反应条件
1: 1.) AgClO4, 4A molecular sieves / 1.) CH2Cl2, RT, 10 min, 2.) CH2Cl2, RT, overnight 2: 76 percent / pyridine / 20 h / Ambient temperature 3: 92 percent / H2 / 5percent Pd/C / methanol; H2O / 90 h / 760 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 48 p. 12474 - 12485
反应条件
1: AcOH / Zn/Cu / tetrahydrofuran 2: aq. CF3COOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 48 p. 15654 - 15655
反应条件
1.1: hydrazine acetate / dimethylformamide 1.2: K2CO3 / CH2Cl2 2.1: TMSOTf; Et2O / CH2Cl2 / -30 °C 3.1: AcOH / Zn/Cu / tetrahydrofuran 4.1: aq. CF3COOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 48 p. 15654 - 15655
反应条件
1: 76 percent / pyridine / 20 h / Ambient temperature 2: 92 percent / H2 / 5percent Pd/C / methanol; H2O / 90 h / 760 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 48 p. 12474 - 12485
反应条件
1: TMSOTf; Et2O / CH2Cl2 / -30 °C 2: AcOH / Zn/Cu / tetrahydrofuran 3: aq. CF3COOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 48 p. 15654 - 15655
反应条件
1.1: TfN3; aq. K2CO3; CuSO4 / CH2Cl2; methanol 2.1: pyridine 3.1: hydrazine acetate / dimethylformamide 3.2: K2CO3 / CH2Cl2 4.1: TMSOTf; Et2O / CH2Cl2 / -30 °C 5.1: AcOH / Zn/Cu / tetrahydrofuran 6.1: aq. CF3COOH View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 48 p. 15654 - 15655
