N-Boc-3-哌啶甲醇合成路线 （共 34 条）
反应条件
triethylamine in tetrahydrofuran T=20°C; 20 h;
参考文献
Batt, Douglas G.
Patent: US2004/67935 A1, 2004 ;
Location in patent: Page/Page column 28 ;
US 20040067935 A1
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h; 2: With Glauber's salt in tetrahydrofuran
参考文献
H. LUNDBECK A/S
Patent: US2011/92475 A1, 2011 ;
Location in patent: Page/Page column 18 ;
参考文献
Bristol-Myers Squibb Company
Patent: US5583146 A1, 1996 ;
US 5583146 A
反应条件
in tetrahydrofuran; water; ethyl acetate
参考文献
ELI LILLY AND COMPANY
Patent: EP806411 A2, 1997 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238
反应条件
1: tetrahydrofuran 2: LAH / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238
反应条件
1: tetrahydrofuran 2: LAH / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 19 h; 2: With sodium hydroxide; water in tetrahydrofuran T=0 - 20°C; 2 h;
参考文献
BIOVITRUM AB (PUBL)
Patent: WO2009/71658 A1, 2009 ;
Location in patent: Page/Page column 33-34 ;
WO 2009/071658 A1
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; 0.5 h; 2: With triethylamine in dichloromethane T=-78 - 20°C; 0.5 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/118531 A1, 2005 ;
Location in patent: Page/Page column 74 ;
WO 2005/118531 A1
