2,6-二甲基-4-苯基-1,4-二氢吡啶-3,5-二羧酸二乙酯合成路线 （共 49 条）
反应条件
1: 38 percent / dioxane / 1 h / Heating
2: 50 percent / KOH / 18 h / Heating
View Scheme
参考文献
Vigante, B. A.; Ozols, Ya. Ya.; Dubur, G. Ya.; Beilis, Yu. I.; Belash, E. M.; Prezhdo, V. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 2 p. 170 - 178
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 2 p. 219 - 228
反应条件
ammonium hydroxide
2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Goerlitzer; Buss
Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949
反应条件
ammonium hydroxide
2 h;
参考文献
Goerlitzer; Buss
Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949
反应条件
in ethanol; acetic acid
1 h; Heating;
参考文献
Krauze, A. A.; Liepin'sh, E. E.; Kalme, Z. A.; Pelcher, Yu. E.; Dubur, G. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 11 p. 1241 - 1245
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , # 11 p. 1504 - 1508
反应条件
in dichloromethane
Ambient temperature; Yield given;
参考文献
Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders
Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268
反应条件
in methanol
16 h; Heating;
参考文献
Memarian, Hamid R.; Abdoli-Senejani, Masumeh; Doepp, Dietrich
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2006 , vol. 61, # 1 p. 50 - 56
反应条件
1: -15 - 0 °C
2: alcohol; ammonia
View Scheme
参考文献
Knoevenagel
Chemische Berichte, 1898 , vol. 31, p. 734
反应条件
1: acetoacetic acid ester / -15 - -5 °C
2: alcohol; ammonia
View Scheme
参考文献
Knoevenagel
Chemische Berichte, 1898 , vol. 31, p. 734
参考文献
Lachowicz
Monatshefte fuer Chemie, 1896 , vol. 17, p. 357
参考文献
Knoevenagel
Chemische Berichte, 1898 , vol. 31, p. 734
