2,6-二甲基-4-苯基-1,4-二氢吡啶-3,5-二羧酸二乙酯合成路线 （共 49 条）
反应条件
in acetic acid; acetonitrile
5 h; Ambient temperature;
参考文献
Singh, Harjit; Singh, Kamaljit
Tetrahedron, 1989 , vol. 45, # 12 p. 3967 - 3974
反应条件
silica gel
Hantzsch synthesis; 0.05 h; microwave irradiation;
参考文献
Yadav; Subba Reddy; Reddy
Synthetic Communications, 2001 , vol. 31, # 3 p. 425 - 430
反应条件
potassium hydroxide
12 h; Heating;
参考文献
Vigante, B. A.; Ozols, Ya. Ya.; Dubur, G. Ya.; Beilis, Yu. I.; Belash, E. M.; Prezhdo, V. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 2 p. 170 - 178
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 2 p. 219 - 228
反应条件
1: SOCl2 / CH2Cl2 / 1 h / 0 °C
2: CH2Cl2 / Ambient temperature
View Scheme
参考文献
Vanden Eynde; D'Orazio; Mayence; Maquestiau; Anders
Tetrahedron, 1992 , vol. 48, # 7 p. 1263 - 1268
反应条件
hydrogenchloride in ethanol
2 h; Heating;
参考文献
Lusis, V. K.; Mutsenietse, D. Kh.; Dubur, G. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 9 p. 1033
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 9 p. 1285 - 1286
反应条件
hydrogenchloride in ethanol
2 h; Heating;
参考文献
Lusis, V. K.; Mutsenietse, D. Kh.; Dubur, G. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 9 p. 1033
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 9 p. 1285 - 1286
反应条件
piperidine; urea
0.666667 h; Heating;
参考文献
Bakibaev, A. A.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4 p. 736 - 740
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 854 - 859
反应条件
acetic acid
Heating;
参考文献
Bakibaev, A. A.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4 p. 740 - 743
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 859 - 863
反应条件
potassium hydroxide
18 h; Heating;
参考文献
Vigante, B. A.; Ozols, Ya. Ya.; Dubur, G. Ya.; Beilis, Yu. I.; Belash, E. M.; Prezhdo, V. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 2 p. 170 - 178
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 2 p. 219 - 228
反应条件
T=70°C; Hantzsch condensation reaction; 1 h; Title compound not separated from byproducts.;
参考文献
Dondoni, Alessandro; Massi, Alessandro; Minghini, Erik; Bertolasi, Valerio
Tetrahedron, 2004 , vol. 60, # 10 p. 2311 - 2326
