(-)-(3Ar,6ar)-3a,6a-二氢-2,2-二甲基-4H-环戊并-1,3-二氧代-4-酮合成路线 （共 63 条）
反应条件
1: With bis(tricyclohexylphosphine)benzylidene ruthenium(IV) dichloride in dichloromethane T=20°C; 4 h; 2: With pyridinium chlorochromate in dichloromethane 12 h;
参考文献
The Trustees of the University of Pennsylvania; Monell Chemical Sense Center
Patent: US2009/76142 A1, 2009 ;
Location in patent: Page/Page column 15 ;
反应条件
1: With bis(tricyclohexylphosphine)benzylidene ruthenium(IV) dichloride in dichloromethane T=20°C; 7 h; 2: With dipyridinium dichromate; acetic acid in dichloromethane T=20°C; 12 h; Molecular sieve;
参考文献
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
Patent: WO2008/124157 A1, 2008 ;
Location in patent: Page/Page column 20 ;
反应条件
manganese(IV) oxide in dichloromethane T=20°C; 6 h;
参考文献
Moon, Hyung Ryong; Choi, Won Jun; Kim, Hea Ok; Jeong, Lak Shin
Tetrahedron Asymmetry, 2002 , vol. 13, # 11 p. 1189 - 1193
反应条件
silica gel in toluene 9 h; Heating;
参考文献
Johnson; Penning
Journal of the American Chemical Society, 1988 , vol. 110, # 14 p. 4726 - 4735
反应条件
RuCl2(tricyclohexylphosphine)2(benzylidene) in dichloromethane T=20°C; 48 h; Inert atmosphere;
参考文献
Kumamoto, Hiroki; Deguchi, Kazuki; Wagata, Tadashi; Furuya, Yuu; Odanaka, Yuki; Kitade, Yukio; Tanaka, Hiromichi
Tetrahedron, 2009 , vol. 65, # 38 p. 8007 - 8013
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-78 - 23°C; 3 h;
参考文献
Smith III, Amos B.; Sperry, Jeffrey B.; Han, Qiang
Journal of Organic Chemistry, 2007 , vol. 72, # 18 p. 6891 - 6900
反应条件
pyridinium chlorochromate in dichloromethane 24 h;
参考文献
Clive, Derrick L. J.; Liu, Dazhan
Journal of Organic Chemistry, 2008 , vol. 73, # 8 p. 3078 - 3087
反应条件
1.1: Ph3P; I2; imidazole 1.2: Zn / methanol 2.1: 80 percent / CH2Cl2; tetrahydrofuran / 3 h / -40 - 0 °C 3.1: Grubbs catalyst / CH2Cl2 4.1: PCC / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 11 p. 3993 - 3996
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide T=60°C; 15 h;
参考文献
Hayashi, Masato; Motosawa, Keiichi; Satoh, Atsushi; Shibuya, Masatoshi; Ogasawara, Kunio; Iwabuchi, Yoshiharu
Heterocycles, 2009 , vol. 77, # 2 p. 855 - 863
反应条件
1: 100 percent / tetrahydrofuran / 1 h / -78 - 20 °C 2: 95 percent / TBAF / tetrahydrofuran / 1 h / 20 °C 3: 97 percent / NaIO4 / H2O / 1 h / 20 °C 4: 86 percent / NaH / dimethylsulfoxide; tetrahydrofuran / 3 h / Heating 5: Grubbs catalyst / CH2Cl2 / 4 h / 24 °C 6: pyridinium chlorochromate; 4 Angstroem molecular sieves; acetic acid / CH2Cl2 / 12 h / 20 °C View Scheme
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 22, # 5-8 p. 771 - 773
