N-苄氧羰基-L-脯氨酸合成路线 （共 150 条）
反应条件
sodium hydroxide in water 13.5 h; Ambient temperature;
参考文献
Takeuchi; Yamada; Suzuki; Koizumi
Tetrahedron, 1996 , vol. 52, # 1 p. 225 - 232
反应条件
hydrogenchloride in sodium hydroxide; toluene
参考文献
Abbott Laboratories
Patent: US5516912 A1, 1996 ;
反应条件
1,4-diaza-bicyclo[2.2.2]octane; hydrogen; palladium on activated charcoal; ethylenediamine in methanol T=20°C; Hydrogenolysis; P=760 Torr; 6 h;
参考文献
Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 2000 , vol. 56, # 43 p. 8433 - 8441
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; trichloroisocyanuric acid; sodium hydrogencarbonate; sodium bromide in water; acetone T=20°C; 24 h;
参考文献
De Luca, Lidia; Giacomelli, Giampaolo; Masala, Simonetta; Porcheddu, Andrea
Journal of Organic Chemistry, 2003 , vol. 68, # 12 p. 4999 - 5001
反应条件
hydrogenchloride; sodium hydroxide; sodium methylate; triethylamine in methanol; water; N,N-dimethyl-formamide
参考文献
Nagashima, Nobuo
Patent: US2003/9056 A1, 2003 ;
反应条件
lithium hydroxide hydrate; water in tetrahydrofuran; methanol T=20°C; 16 h;
参考文献
WO2013/131018 A1, ;
Page/Page column 43; 44 ;
反应条件
in methanol; water; ethyl acetate; Petroleum ether
参考文献
Societe Nationale des Poudres et Explosifs
Patent: US4725680 A1, 1988 ;
反应条件
water; triethylamine in 1,4-dioxane T=20°C; Acylation; 3 h;
参考文献
Yasuhara, Tomohisa; Nagaoka, Yasuo; Tomioka, Kiyoshi
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 16 p. 2233 - 2234
反应条件
in chloroform; water; triethylamine 5 h; Ambient temperature;
参考文献
Effenberger, Franz; Brodt, Werner
Chemische Berichte, 1985 , vol. 118, # 2 p. 468 - 482
反应条件
Candida antarctica lipase in phosphate buffer T=30°C; 38 h;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 10 p. 1323 - 1333
