5-(3,4-二甲氧基苯基)戊酸合成路线 （共 7 条）
反应条件
sodium hydroxide in ethanol T=20°C; 12 h;
参考文献
Magrioti, Victoria; Nikolaou, Aikaterini; Smyrniotou, Annetta; Shah, Ishita; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5823 - 5829
反应条件
hydrogenchloride; acetic acid; mercury; zinc in water; toluene 16 h; Heating;
参考文献
Singh
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 3 p. 215 - 218
反应条件
1: 10.4 percent / AlCl3 / nitrobenzene 2: 81.8 percent / triethylsilane / trifluoroacetic acid / 0 - 20 °C View Scheme
参考文献
Singh
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 3 p. 215 - 218
反应条件
1: AlCl3 / nitrobenzene / Ambient temperature 2: H2 / Pd/C / acetic acid / 65 °C View Scheme
参考文献
Mihova, Tonya R.; Linden, Anthony; Heimgartner, Heinz
Heterocycles, 1998 , vol. 49, # 1 p. 215 - 232
反应条件
1: platinum; ethanol / Hydrogenation 2: 180 °C / 18 Torr View Scheme
参考文献
Gardner et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 5527
反应条件
1: palladium 10 on activated carbon; hydrogen / ethanol / 12 h 2: sodium hydroxide / ethanol / 12 h / 20 °C View Scheme
参考文献
Magrioti, Victoria; Nikolaou, Aikaterini; Smyrniotou, Annetta; Shah, Ishita; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5823 - 5829
反应条件
1: lithium hydroxide hydrate / tetrahydrofuran / 24 h / |Molecular sieve; |Inert atmosphere; |Reflux 2: palladium 10 on activated carbon; hydrogen / ethanol / 12 h 3: sodium hydroxide / ethanol / 12 h / 20 °C View Scheme
参考文献
Magrioti, Victoria; Nikolaou, Aikaterini; Smyrniotou, Annetta; Shah, Ishita; Constantinou-Kokotou, Violetta; Dennis, Edward A.; Kokotos, George
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5823 - 5829
