in water T=23°C; 3 h;

triethylamine in dichloromethane T=30°C; 3 h;

lithium aluminium tetrahydride in diethyl ether 1.16667 h; Heating;

1: 75 percent / CHCl3 / 0.5 h / Ambient temperature 2: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C 3: 96 percent / potassium ethoxide / ethanol / 3 h / Heating View Scheme

1: 75 percent / CHCl3 / 0.5 h / Ambient temperature 2: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C View Scheme

1: 75 percent / CHCl3 / 0.5 h / Ambient temperature 2: 49 percent / polyphosphoric acid / 1 h / 70 - 80 °C 3: 61 percent / lithium aluminum hydride / tetrahydrofuran / 20 h / Heating 4: 1.) 5percent Pd/C, 2.) 15percent aq. NaCl / 1.) glacial acetic acid, reflux, 20 h, 2.) water, ethanol View Scheme

1: 25 percent / CHCl3 / 0.5 h / Ambient temperature 2: 30 percent / 4 h / 220 °C 3: 95 percent / lithium aluminum hydride / tetrahydrofuran / 24 h / Heating 4: 1.) 5percent Pd/C, 2.) 15percent aq. NaCl / 1.) glacial acetic acid, reflux, 40 h, 2.) water View Scheme

1: LiALH4 / diethyl ether / 1.17 h / Heating 2: 65 percent / (aq) NaOH / diethyl ether / 1.83 h / -6 °C View Scheme

in chloroform 0.5 h; Ambient temperature;