(反式)-1,1'-(1,2-环丙烷二基)二苯合成路线 （共 61 条）
反应条件
in 1,4-dioxane
12 h; Heating; Yield given;
参考文献
O'Connor,E.J.; Brandt,S.; Helquist,P.
Journal of the American Chemical Society, 1987 , vol. 109, p. 3739
反应条件
1: H2O
2: 1) n-BuLi, 2) D2O / tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Fox, Marye Anne; Chen, Chia-Chung; Campbell, Kay A.
Journal of Organic Chemistry, 1983 , vol. 48, # 3 p. 321 - 326
反应条件
N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine in N,N-dimethyl-formamide
T=20°C; 90 h; Inert atmosphereUV-irradiation;
参考文献
Cahard, Elise; Schoenebeck, Franziska; Garnier, Jean; Cutulic, Sylvain P. Y.; Zhou, Shengze; Murphy, John A.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 15 p. 3673 - 3676
反应条件
bis(acetylacetonate)nickel(II); methyllithium in tetrahydrofuran; diethyl ether
T=65°C; 8 h;
参考文献
Gai, Yonghua; Julia, Marc; Verpeaux, Jean-Noel
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 9 p. 817 - 829
反应条件
1: 15 percent
2: 1) n-BuLi / 1) THF, -78 deg C, 2) -78 to 20 deg C, 1 h
3: n-BuLi / tetrahydrofuran; pentane / 0.7 h / -78 °C
View Scheme
参考文献
Krief, Alain; Hobe, Myriam; Dumont, Willy; Badaoui, Elie; Guittet, Eric; Evrard, Guy
Tetrahedron Letters, 1992 , vol. 33, # 23 p. 3381 - 3384
反应条件
1: 85percent hydrazine hydrate / 1 h / Heating
2: KOH / bis-(2-hydroxy-ethyl) ether / 0.75 h / 200 - 230 °C
View Scheme
参考文献
Applequist, Douglas E.; Gdanski, Rick D.
Journal of Organic Chemistry, 1981 , vol. 46, # 12 p. 2502 - 2510
反应条件
N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine in N,N-dimethyl-formamide
T=20°C; 11 h; Inert atmosphereUV-irradiation;
参考文献
Cahard, Elise; Schoenebeck, Franziska; Garnier, Jean; Cutulic, Sylvain P. Y.; Zhou, Shengze; Murphy, John A.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 15 p. 3673 - 3676
反应条件
bis(acetylacetonate)nickel(II); methyllithium in tetrahydrofuran; diethyl ether
T=65°C; 10 h; Yield given. Yields of byproduct given;
参考文献
Gai, Yonghua; Julia, Marc; Verpeaux, Jean-Noel
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 9 p. 817 - 829
反应条件
bis(acetylacetonate)nickel(II); methyllithium in tetrahydrofuran; diethyl ether
T=65°C; 8 h; Yields of byproduct given;
参考文献
Gai, Yonghua; Julia, Marc; Verpeaux, Jean-Noel
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 9 p. 817 - 829
反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 2) -78 to 20 deg C, 1 h
2: n-BuLi / tetrahydrofuran; pentane / 0.7 h / -78 °C
View Scheme
参考文献
Krief, Alain; Hobe, Myriam; Dumont, Willy; Badaoui, Elie; Guittet, Eric; Evrard, Guy
Tetrahedron Letters, 1992 , vol. 33, # 23 p. 3381 - 3384
