N,N-二甲基-4-联苯胺合成路线 （共 82 条）
反应条件
Ni(PCy3)2Cl2; potassium carbonate; tri-cyclo-hexyl-phosphine in 1,4-dioxane; water
T=110°C; Suzuki-Miyaura coupling; 16 h; Inert atmosphere;
参考文献
Xu, Li; Li, Bi-Jie; Wu, Zhen-Hua; Lu, Xing-Yu; Guan, Bing-Tao; Wang, Bi-Qin; Zhao, Ke-Qing; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 4 p. 884 - 887
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; ethylene glycol dimethyl ether in tetrahydrofuran
T=20°C; 1 h;
参考文献
Riguet, Eric; Alami, Mouad; Cahiez, Gerard
Journal of Organometallic Chemistry, 2001 , vol. 624, # 1-2 p. 376 - 379
反应条件
sodium tetrahydroborate; sulfuric acid in tetrahydrofuran
T=-10°C;
参考文献
Azzena, Ugo; Cattari, Manuela; Melloni, Giovanni; Pisano, Luisa
Synthesis, 2003 , # 18 p. 2811 - 2814
反应条件
stilbazo; palladium diacetate; potassium carbonate in water
T=20°C; Suzuki-Miyaura cross-coupling reaction; Inert atmosphere;
参考文献
Peng, Yi-Yuan; Liu, Jinbiao; Lei, Xiaoli; Yin, Zenlan
Green Chemistry, 2010 , vol. 12, # 6 p. 1072 - 1075
反应条件
catalyst 1 (aliphatic, phosphine based pincer complex of palladium) in 1,4-dioxane; 1-methyl-pyrrolidin-2-one
T=100°C; Negishi cross-coupling reaction; 0.25 h;
参考文献
Gerber, Roman; Blacque, Olivier; Frech, Christian M.
Dalton Transactions, 2011 , vol. 40, # 48 p. 12939 - 12941
反应条件
[iridium(III)(2-phenylpyridine)3]; potassium tert-butylate in dimethyl sulfoxide
T=80°C; 36 h; Schlenk techniqueInert atmosphereIrradiation;
参考文献
Cheng, Yannan; Gu, Xiangyong; Li, Pixu
Organic Letters, 2013 , vol. 15, # 11 p. 2664 - 2667
反应条件
1: bromobenzene With lithium in diethyl ether
2: With zinc(II) chloride in tetrahydrofuran; diethyl ether
T=20°C; 1 h;
3: 4-Me2NC6H4Cl With nickel phosphine amido pincer complex in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=70°C; 3 h; Further stages.;
参考文献
Wang, Li; Wang, Zhong-Xia
Organic Letters, 2007 , vol. 9, # 21 p. 4335 - 4338
反应条件
C27H22Cl2N3NiP in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
12 h; Inert atmosphereSchlenk techniqueHeating;
参考文献
Zhang, Qiang; Zhang, Xue-Qi; Wang, Zhong-Xia
Dalton Transactions, 2012 , vol. 41, # 34 p. 10453 - 10464,12
反应条件
trifluoroacetic acid; trifluoroacetic anhydride in benzene
T=30°C;
参考文献
Shudo, Koichi; Ohta, Toshiharu; Okamoto, Toshihiko
Journal of the American Chemical Society, 1981 , vol. 103, # 3 p. 645 - 653
反应条件
tris-(o-tolyl)phosphine; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in toluene
T=100°C;
参考文献
Guram, Anil S.; Rennels, Roger A.; Buchwald, Stephen L.
Angewandte Chemie, 1995 , vol. 107, # 12 p. 1456 - 1459
