3',4',5'-三甲氧基苯乙酮合成路线 （共 90 条）
反应条件
copper(l) iodide; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; potassium tert-butylate; L-proline in N,N-dimethyl-formamide T=25°C; 5 h;
参考文献
Zhang, Guofu; Han, Xingwang; Luan, Yuxin; Wang, Yong; Wen, Xin; Ding, Chengrong
Chemical Communications, 2013 , vol. 49, # 72 p. 7908 - 7910
反应条件
iron(III) sulphate hydrate; acetic acid T=95°C; 24 h; Schlenk technique;
参考文献
Bassetti, Mauro; Ciceri, Samuele; Lancia, Federico; Pasquini, Chiara
Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1608 - 1612
反应条件
1: With tert.-butylnitrite in benzene Nitrosation; 2: in benzene T=0°C; Elimination; Photolysis; Further stages.;
参考文献
Paredes; Alonso
Journal of Organic Chemistry, 2000 , vol. 65, # 8 p. 2292 - 2304
反应条件
perchloric acid; oxygen; palladium diacetate; p-benozquinone; sodium nitrite in methanol; water T=20°C; Wacker Oxidation; 24 h; Schlenk techniqueSealed tubeGreen chemistry;
参考文献
Zhang, Guofu; Xie, Xiaoqiang; Wang, Yong; Wen, Xin; Zhao, Yun; Ding, Chengrong
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 18 p. 2947 - 2950
反应条件
magnesium in tetrahydrofuran T=20°C; Grignard reaction; 1.33333 h; Reflux;
参考文献
Saxena, Hari Om; Faridi, Uzma; Srivastava, Suchita; Kumar; Darokar; Luqman, Suaib; Chanotiya; Krishna, Vinay; Negi, Arvind S.; Khanuja
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 14 p. 3914 - 3918
反应条件
tris(triphenylphosphine)ruthenium(II) chloride; potassium 2-methyl-2-butoxide; ethyl acetate in toluene T=140°C; 18 h; Schlenk techniqueSealed tubeInert atmosphere; chemoselective reaction;
参考文献
ChemCatChem, , vol. 5, # 8 p. 2170 - 2173
反应条件
ozone; acetic acid T=50°C;
参考文献
Journal of the American Chemical Society, , vol. 36, p. 518
反应条件
dichloro bis(acetonitrile) palladium(II); water; oxygen; copper dichloride in toluene; tert-butyl alcohol T=60°C; Wacker Oxidation; P=6000.6 Torr; 1 h; Flow reactor;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 10 p. 1905 - 1910
参考文献
Journal of the American Chemical Society, , vol. 80, p. 5756,5766
反应条件
1.1: 84 percent / tetrahydrofuran / -78 - 0 °C 2.1: 91 percent / DMSO; oxalyl chloride; Et3N / CH2Cl2 / -78 °C 3.1: 94 percent / tetrahydrofuran; diethyl ether / -78 °C 4.1: t-BuONO / benzene 4.2: 77 percent / benzene / 0 °C / Photolysis View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 8 p. 2292 - 2304
