sodium phosphate-citrate buffer; β-glucosidase T=37°C; 24 h;

sodium phosphate-citrate buffer; β-glucosidase T=37°C; 24 h;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: n-buthyllithium / hexane; tetrahydrofuran / 0.17 h / -65 &deg;C<br />1.2: triisopropyl borate / tetrahydrofuran / 0.17 h / -65 &deg;C<br />1.3: hydrochloric acid / H₂O<br />2.1: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />3.1: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 100 percent / 4-N,N-dimethylaminopyridine; pyridine / 1 h / 20 &deg;C<br />2: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />3: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 68 percent / immobilized β-D-glucosidase / 72 h / 50 &deg;C<br />2: 100 percent / 4-N,N-dimethylaminopyridine; pyridine / 1 h / 20 &deg;C<br />3: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />4: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: 75 percent / hydrochloric acid / acetonitrile / 24 h / 20 &deg;C<br />2.1: n-buthyllithium / hexane; tetrahydrofuran / 0.17 h / -65 &deg;C<br />2.2: triisopropyl borate / tetrahydrofuran / 0.17 h / -65 &deg;C<br />2.3: hydrochloric acid / H₂O<br />3.1: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />4.1: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />2: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 42 percent / copper(II) acetate; lithium acetate; palladium(II) acetate / dimethylformamide / 0.5 h / 80 &deg;C<br />2: 99 percent / NaOMe / methanol / 1 h<br /> <br /> &nbsp;