6,7,8,9-四氢-二苯并呋喃-2-醇合成路线 （共 9 条）
反应条件
1: in toluene
T=0°C; 8 h; Inert atmosphere;
2: With hydrogenchloride in water
6.5 h; Inert atmosphere;
参考文献
Kelgtermans, Hans; Dobrzanska, Liliana; Van Meervelt, Luc; Dehaen, Wim
Tetrahedron, 2011 , vol. 67, # 20 p. 3685 - 3689
反应条件
sodium iodide in acetonitrile
T=70°C; 30 h;
参考文献
Bachelet, Jean-Pierre; Caubere, Paul
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 234 - 238
反应条件
lithium perchlorate in diethyl ether
Ambient temperature;
参考文献
Saraswathy, V. Geetha; Sankararaman, S.
Journal of Organic Chemistry, 1995 , vol. 60, # 16 p. 5024 - 5028
反应条件
1: NaNH2-t-BuONa / 24 h / 40 °C
2: 82 percent / Me3Si, NaI / acetonitrile / 30 h / 70 °C
View Scheme
参考文献
Bachelet, Jean-Pierre; Caubere, Paul
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 234 - 238
反应条件
1: NaNH2-t-BuONa / 24 h / 40 °C
2: 82 percent / Me3Si, NaI / acetonitrile / 30 h / 70 °C
View Scheme
参考文献
Bachelet, Jean-Pierre; Caubere, Paul
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 234 - 238
反应条件
in acetic acid
1 h; Heating;
参考文献
Kucklaender, Uwe; Toeberich, Hildegard; Kuna, Krystina
Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 4 p. 312 - 317
反应条件
hydrogenchloride; sodium amide; sodium t-butanolate
1.) 40 deg C, 24 h, 2.) acetone, 20 deg C, 3h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Bachelet, Jean-Pierre; Caubere, Paul
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 234 - 238
反应条件
in acetic acid
24 h;
参考文献
Kucklaender, Uwe; Toeberich, Hildegard; Kuna, Krystina
Archiv der Pharmazie (Weinheim, Germany), 1987 , vol. 320, # 4 p. 312 - 317
反应条件
1: With zinc(II) chloride in dichloromethane
Friedel-Crafts alkylation; 9 h; Inert atmosphereReflux;
2: With water in dichloromethane
参考文献
Kelgtermans, Hans; Dobrzanska, Liliana; Van Meervelt, Luc; Dehaen, Wim
Tetrahedron, 2011 , vol. 67, # 20 p. 3685 - 3689
