甲基2-{(E)-[(二甲基氨基)亚甲基]氨基}苯甲酸酯合成路线 （共 13 条）
反应条件
T=85 - 90°C; Neat (no solvent);
参考文献
Tetrahedron Letters, , vol. 53, # 32 p. 4062 - 4064
反应条件
1.1: tetrahydrofuran / -78 °C 1.2: AcOH / 20 °C 2.1: POCl3 / Heating View Scheme
参考文献
Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828
反应条件
T=85 - 90°C; Neat (no solvent);
参考文献
Jalani, Hitesh B.; Pandya, Amit N.; Pandya, Dhaivat H.; Sharma, Jayesh A.; Sudarsanam; Vasu, Kamala K.
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4062 - 4064
反应条件
T=85 - 90°C; Neat (no solvent);
参考文献
Jalani, Hitesh B.; Pandya, Amit N.; Pandya, Dhaivat H.; Sharma, Jayesh A.; Sudarsanam; Vasu, Kamala K.
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4062 - 4064
反应条件
toluene-4-sulfonic acid in 1,4-dioxane 2 h; Heating;
参考文献
Gupton, John T.; Miller, John F.; Bryant, Robert D.; Maloney, Patrick R.; Foster, Bruce S.
Tetrahedron, 1987 , vol. 43, # 8 p. 1747 - 1752
反应条件
T=85 - 90°C; Neat (no solvent);
参考文献
Jalani, Hitesh B.; Pandya, Amit N.; Pandya, Dhaivat H.; Sharma, Jayesh A.; Sudarsanam; Vasu, Kamala K.
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4062 - 4064
反应条件
hydrogenchloride; sodium methylate in water; toluene; acetonitrile
参考文献
American Cyanamid Company
Patent: US6288082 B1, 2001 ;
反应条件
1: With sodium methylate in toluene
18 h; Heating / reflux;
2: With hydrogenchloride in water; toluene
pH=3;
参考文献
Wyeth Holdings Corporation
Patent: EP1117659 B1, 2003 ;
Location in patent: Page 57 ;
反应条件
1: in tetrahydrofuran
T=-78°C;
2: With acetic acid
T=20°C;
参考文献
Zhang, Nan; Wu, Biqi; Powell, Dennis; Wissner, Allan; B. Floyd, Middleton; D. Kovacs, Eleonora; Toral-Barza, Lourdes; Kohler, Constance
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2825 - 2828
反应条件
acetic acid
T=100°C; 0.25 h; Microwave irradiation;
参考文献
Deau, Emmanuel; Hedou, Damien; Chosson, Elizabeth; Levacher, Vincent; Besson, Thierry
Tetrahedron Letters, 2013 , vol. 54, # 27 p. 3518 - 3521
