3,5-二甲氧基苯甲酸合成路线 （共 127 条）
反应条件
in methanol; diethyl ether
参考文献
Roblot, F.; Hocquemiller, R.; Cave, A.
Bulletin de la Societe Chimique de France, 1990 , # 2 p. 258 - 267
反应条件
in methanol; diethyl ether; benzene 0.5 h;
参考文献
Maresh, Justin; Zhang, Jin; Tzeng, Yih-Ling; Goodman, Nora A.; Lynn, David G.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3281 - 3286
反应条件
1: SOCl2 View Scheme
参考文献
Broehmer, Manuel C.; Mundinger, Stephan; Braese, Stefan; Bannwarth, Willi
Angewandte Chemie - International Edition, 2011 , vol. 50, # 27 p. 6175 - 6177
反应条件
potassium carbonate in acetone
参考文献
Eiden; Meins
Archiv der Pharmazie, 1972 , vol. 305, # 2 p. 124 - 134
反应条件
N'',N'''''-1,8-naphthalenediyl-bis[N,N,N',N'-tetramethyl]-guanidine in N,N-dimethyl-formamide T=20°C; Kinetics;
参考文献
Gholamipour-Shirazi, Azarmidokht; Rolando, Christian
Organic Process Research and Development, 2012 , vol. 16, # 5 p. 811 - 818
参考文献
Wang, Liang; Dai, Fu-Ying; Zhu, Jie; Dong, Kui-Kui; Wang, Yu-Liang; Chen, Tian
Journal of Chemical Research, 2011 , vol. 35, # 5 p. 313 - 316
反应条件
1: 97 percent / LiAlH4 / tetrahydrofuran / 1 h / Heating 2: 1.) MeLi / 1.) THF, ether, -10 deg C, 0.5 h, 2.) THF, -10 deg C, 1 h. 3: 91 percent / tetrahydrofuran; hexane / 0.17 h / -10 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: phosphorus pentachloride 2: carbon disulfide; aluminium chloride View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 87, p. 415
反应条件
1: 87 percent / HNO3, acetic anhydride / acetic acid 2: 69 percent / FeSO4, NH3 3: 1.) aq. NaNO3, concd. H2SO4, 2.) aq. KI / 1.) water, 0 deg C, 2.) reflux, 30 min View Scheme
参考文献
Insole, Joan M.
Journal of Chemical Research, Miniprint, 1990 , # 12 p. 2831 - 2867
反应条件
1: 3,5-(MeO)2C6H3COOH With sodium in ammonia Birch reduction; 2: 2-(phenyl)ethyl bromide in ammonia
参考文献
Castanedo, Ricardo; Covarrubias-Zuniga, Adrian; Maldonado, Luis A.
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 973 - 976
