N-(叔-丁基氧羰基)-N-[(1S,2R)-2-羟基-1,2-二苯基乙基]-甘氨酸乙酯合成路线 (共 5 条)
反应条件
1: Et3N / tetrahydrofuran / 1 h / 20 °C 2: toluene / 10 h / Heating View Scheme
参考文献
Synlett, , # 4 art. no. Y04304ST, p. 693 - 696
反应条件
sodium hydrogencarbonate; sodium chloride in chloroform; water 20 h; Heating;
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557
反应条件
1: 73.4 percent / p-toluenesulfonic acid monohydrate, CaCl2 / benzene / 8 h / Heating 2: N-bromosuccinimide / CCl4 / 1 h / Heating 3: 63 percent / ZnCl2 / tetrahydrofuran / 4 h 4: 71 percent / Li, NH3 / ethanol; tetrahydrofuran / 0.25 h / -33 °C View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
toluene-4-sulfonic acid; calcium chloride in benzene 8 h; Heating;
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
1: 73.4 percent / p-toluenesulfonic acid monohydrate, CaCl2 / benzene / 8 h / Heating 2: N-bromosuccinimide / CCl4 / 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557