2,3-二氯-N-甲基马来酰亚胺顺丁烯二酰亚胺合成路线 （共 8 条）
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 3109 - 3113
反应条件
ethylmagnesium bromide in tetrahydrofuran; toluene T=90°C;
参考文献
Heterocycles, , vol. 53, # 10 p. 2119 - 2122
反应条件
in diethyl ether; toluene 24 h; Yield given;
参考文献
Synthesis, , # 12 p. 1511 - 1516
反应条件
in diethyl ether; toluene 24 h; Heatingfurther solvents; further indole derivatives and dihalomaleimides; Product distribution;
参考文献
Synthesis, , # 12 p. 1511 - 1516
反应条件
1: With acetic acid
2: With sodium methylate
T=20°C; Reflux;
参考文献
Delarue-Cochin, Sandrine; McCort-Tranchepain, Isabelle
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 4 p. 706 - 716
反应条件
N-methylamine hydrochloride; sodium methylate; acetic acid in water
参考文献
Eli Lilly and Company
Patent: US5859261 A1, 1999 ;
反应条件
in water; acetic acid
Substitution; 5.5 h; Heating;
参考文献
Slater, Martin J.; Cockerill, Stuart; Baxter, Robert; Bonser, Robert W.; Gohil, Kam; Gowrie, Clare; Robinson, J. Edward; Littler, Edward; Parry, Nigel; Randall, Roger; Snowden, Wendy
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 6 p. 1067 - 1074
反应条件
pyridine; thionyl chloride
Chlorination;
参考文献
Brisse, Francois; Atfani, Mohamed; Bergeron, Jean-Yves; Belanger-Gariepy, Francine; Armand, Michel
Acta Crystallographica Section C: Crystal Structure Communications, 2000 , vol. 56, # 2 p. 190 - 192
