5-(2-氨基丙基)-2-甲氧基苯磺酰胺合成路线 （共 4 条）
反应条件
hydrogen; nickel in methanol T=20°C; P=2942.29 Torr; 8 h;
参考文献
WO2004/58694 A1, ;
Page 6 ;
反应条件
ammonium acetate; sodium cyanoborohydride in methanol T=20°C; 15 h;
参考文献
Sagratini, Gianni; Angeli, Piero; Buccioni, Michela; Gulini, Ugo; Marucci, Gabriella; Melchiorre, Carlo; Poggesi, Elena; Giardin, Dario
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 12 p. 5800 - 5807
反应条件
in N-methyl-acetamide; water
参考文献
Hoorn, Hans J.; Peters, Theodorus H.A.; Pis, Jaroslav; Scigel, Radim
Patent: US2003/109752 A1, 2003 ;
反应条件
optical-resolution agent; diethylamine in methanol; ethanol T=40°C; Optical-resolution column; Purification / work up;
参考文献
SANYO CHEMICAL LABORATORY CO., LTD.
Patent: JP2005/247811 A, 2005 ;
Location in patent: Page/Page column 8 ;
