2,6-二甲基吡啶-3-醇合成路线 （共 12 条）
反应条件
1: rac-2-(Trifluormethylsulfonyloxy)propionsaeure-ethylester; acetonitrile With trimethylsilyl trifluoromethanesulfonate in acetonitrile T=130°C; Inert atmosphereMicrowave irradiationSealed tube; 2: acrylic acid With triethylamine in acetonitrile T=150°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
Journal of Organic Chemistry, , vol. 79, # 3 p. 1303 - 1319
反应条件
methanol; palladium on activated charcoal
参考文献
Journal of the American Chemical Society, , vol. 71, p. 2968,2971
反应条件
1: water; hydrobromic acid 2: palladium/charcoal; methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 71, p. 2968,2971
反应条件
ammonium hydroxide T=130 - 135°C;
反应条件
1: Raney Ni alloy, 2 N aq. NaOH / ethanol / 1 h / Ambient temperature 2: 1.) oxygen, tetraphenylporphine, 2.) triphenylphosphine / 1.) CH2Cl2, -70 deg C, irradiation, 2 h, 2.) -70 deg C, 10 min View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 181 - 183
反应条件
sulfuric acid Natriumnitrit hergestellten Diazoniumsalz-Loesung mit Wasser;
参考文献
Chemische Berichte, , vol. 72, p. 577,579
Yakugaku Zasshi, , vol. 61, p. 230,232; dtsch. Ref. Nr. 6, S. 91, 94
Chem.Abstr., , p. 2941
反应条件
1: aq.-ethanolic H2SO4 / elektrochemische Reduktion an einer Kupfer-Kathode 2: aqueous hydrochloric acid / Natriumnitrit hergestellten Diazoniumsalz-Loesung mit Wasser View Scheme
参考文献
Yakugaku Zasshi, , vol. 61, p. 230,232; dtsch. Ref. Nr. 6, S. 91, 94
Chem.Abstr., , p. 2941
反应条件
oxygen; 5,15,10,20-tetraphenylporphyrin; triphenylphosphine 1.) CH2Cl2, -70 deg C, irradiation, 2 h, 2.) -70 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 181 - 183
反应条件
ethanol; platinum Hydrogenation;
参考文献
Journal of the Chemical Society, , p. 560,562
反应条件
1: water; NaOH-solution 2: chloroform; thionyl chloride 3: platinum; ethanol / Hydrogenation View Scheme
参考文献
Journal of the Chemical Society, , p. 560,562
