反应条件
1: 1,10-dihydroxydecane With [3H]-L-Alanine; L-alanine dehydrogenase; ω-transaminase from Chromobacterium violaceum; alcohol dehydrogenase from Bacillus stearothermophilus; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; ammonium chloride; sodium hydroxide in ethylene glycol dimethyl ether; water
T=25°C; pH=8.5; 20 h; Enzymatic reaction;
2: O-carbethoxy-N-hydroxysuccinimide With triethylamine in water; acetonitrile
T=45°C; 1 h;
参考文献
Sattler, Johann H.; Fuchs, Michael; Tauber, Katharina; Mutti, Francesco G.; Faber, Kurt; Pfeffer, Jan; Haas, Thomas; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9156 - 9159
Angew. Chem., 2012 , vol. 124, # 36 p. 9290 - 9293