N,N-二甲基甘氨酸合成路线

参考文献

Pharmacia and Upjohn Company
Patent: US5652238 A1, 1997 ;

1240137-87-4N-((s)-1-氨基-3-(4-(8-((s)-1-羟基乙基)咪唑并[1,2-a]吡啶-2-基)苯基)丙烷-2-基)-3-氯-4-异丙氧基苯甲酰胺

1088965-37-03-氯-n-((s)-1-(2-(二甲基氨基)乙酰氨基)-3-(4-(8-((s)-1-羟基乙基)咪唑并[1,2-a]吡啶-2-基)苯基)丙烷-2-基)-4-异丙氧基苯甲酰胺

参考文献

Bellingham, Richard; Buswell, A. Mark; Choudary, Bernie M.; Gordon, Andrew H.; Moore, Steve O.; Peterson, Matthew; Sasse, Mike; Shamji, Amin; Urquhart, Michael W. J.
Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1254 - 1263

1118-68-9N,N-二甲基甘氨酸+

634-20-82-乙酰氧基苯基甲烷二醇二乙酸酯

78400-37-0

参考文献

Ito; Abe; Sasaki; Misono
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 7 p. 2175 - 2176

1118-68-9N,N-二甲基甘氨酸+

90-02-8水杨醛

634-20-82-乙酰氧基苯基甲烷二醇二乙酸酯+

78400-37-0

参考文献

Ito; Abe; Sasaki; Misono
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 7 p. 2175 - 2176

1118-68-9N,N-二甲基甘氨酸+

143-15-7溴代十二烷

92829-25-9

参考文献

Minch,M.J. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 31 - 33

1118-68-9N,N-二甲基甘氨酸

60853-81-8二甲基氨基氯化氢

参考文献

Martin, Richard; Flatt, Brenton Todd; Kahl, Jeffrey Dean; Wang, Tie-Lin
Patent: US2003/212111 A1, 2003 ;
US 20030212111 A1

1118-68-9N,N-二甲基甘氨酸+

90-02-8水杨醛

634-20-82-乙酰氧基苯基甲烷二醇二乙酸酯+

78400-37-0

参考文献

Ito; Abe; Sasaki; Misono
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 7 p. 2175 - 2176

1118-68-9N,N-二甲基甘氨酸

51552-16-0(二甲基氨基)乙酰氯

参考文献

Li, Hong-Yu; Wang, Yan; Yan, Lei; Campbell, Robert M.; Anderson, Bryan D.; Wagner, Jill R.; Yingling, Jonathan M.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3585 - 3588