1: KOH 2: H2 / Pd/CaCO3 / cyclohexane View Scheme

1: 28 percent / SeO2, tert-butyl-hydroperoxid (TBHP) / CH2Cl2; H2O / 18 h / 0 °C 2: 92 percent / tetrahydrofuran / 4 h / Ambient temperature 3: 95 percent / pyridin / 2 h 4: PBr3, pyridine / petroleum ether / 3 h / -17 °C 5: 45 percent / dimethylformamide / 16 h / 60 °C 6: 80 percent / K2CO3 / methanol / 3 h / Ambient temperature 7: 57 percent / tert-Butyl-hydroperoxid (TBHP), Molekularsieb 4 Angstroem, Ti(i-OPr)4, (-)-D-Diethyl-tartrat / CH2Cl2; toluene / 4 h / -40 - -20 °C 8: 81 percent / Pyridin / 16 h / 0 °C 9: NaI / acetone / 2 h / 60 °C 10: 48 percent / Na(BH3CN) / tetrahydrofuran; hexamethylphosphoric acid triamide / 24 h / Ambient temperature 11: 44 percent / BuLi / hexane 12: 57 percent 13: 68 percent View Scheme

1: 288 mg 2: lithium aluminium hydride 3: phosphorus tribromide View Scheme

sodium tetrahydroborate in methanol T=0°C;

yeast WAT11 strain transfected with full-length CYP82G1 cDNA cloned into modified YEp352 gateway vector Enzymatic reaction;

1: 288 mg 2: lithium aluminium hydride 3: phosphorus tribromide 4: sodium / ethanol View Scheme

ammonia ueber mehrere Stufen;