water; trifluoroacetic acid T=20°C; Hydrolysis;

1: H2 / 10percent Ru/C / methanol / 24 h / 50 °C / 2250.2 Torr 2: 1.) KOH / 1.) DMSO, 10 min, 2.) DMSO, room temperature, 2 h 3: 70.7 percent / H2 / Pd/C / methanol / 2 h / 50 °C 4: 80.4 percent / oxalyl chloride View Scheme

1: 70.7 percent / H2 / Pd/C / methanol / 2 h / 50 °C 2: 80.4 percent / oxalyl chloride View Scheme

1: 1.) KOH / 1.) DMSO, 10 min, 2.) DMSO, room temperature, 2 h 2: 70.7 percent / H2 / Pd/C / methanol / 2 h / 50 °C 3: 80.4 percent / oxalyl chloride View Scheme

1: 80 percent / KH / tetrahydrofuran / 0 - 20 °C 2: 90 percent / bis(trifluoroacetoxy)iodobenzene / 20 °C 3: 89 percent / TFA; H2O / 20 °C View Scheme