1: (1-(tert-butoxycarbonyl)-(4S)-fluoro-(2R)-pyrrolidinyl)acetonitrile With sodium t-butanolate in tetrahydrofuran T=0°C; 0.5 h; 2: allyl bromide in tetrahydrofuran T=0°C; 3 h;

1: methyl allyl carbonate With 1,4-diaza-bicyclo[2.2.2]octane; di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; C37H32NO3P in tetrahydrofuran 0.333333 h; 2: (1-(tert-butoxycarbonyl)-(4S)-fluoro-(2R)-pyrrolidinyl)acetonitrile in tetrahydrofuran T=50°C; 48 h; Inert atmosphere;