4-甲基嘧啶-5-甲酸乙酯合成路线 （共 9 条）
反应条件
ammonium acetate; zinc(II) chloride in toluene T=100°C; 5 h; Inert atmosphere;
参考文献
Sasada, Toshiaki; Kobayashi, Fuminori; Sakai, Norio; Konakahara, Takeo
Organic Letters, 2009 , vol. 11, # 10 p. 2161 - 2164
反应条件
sodium ethanolate in ethanol 6 h; Reflux;
参考文献
WO2011/42797 A1, ;
Page/Page column 69 ;
反应条件
sodium ethanolate in ethanol 0 deg C, 1 h, 0 deg C to RT, reflux, 1 h;
参考文献
Bulletin de la Societe Chimique de France, , # 2 p. 318 - 324
反应条件
in acetonitrile 6 h; Heating;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 28, # 9 p. 1054 - 1059
Khimiya Geterotsiklicheskikh Soedinenii, , # 9 p. 1243 - 1249
反应条件
in acetonitrile 6 h; Heating;
参考文献
Doklady Chemistry, , vol. 292, p. 12 - 15
Dokl. Akad. Nauk SSSR Ser. Khim., , vol. 292, # 2 p. 364 - 369
反应条件
in acetonitrile 6 h; Heating; Mechanism;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 28, # 9 p. 1054 - 1059
Khimiya Geterotsiklicheskikh Soedinenii, , # 9 p. 1243 - 1249
反应条件
hydrogenchloride in methanol; water 7 h; Heating;
参考文献
Bulletin de la Societe Chimique de France, , # 2 p. 318 - 324
反应条件
1: With water; sodium hydroxide Reflux; 2: With hydrogenchloride in water T=25 - 28°C;
参考文献
ICOZEN THERAPEUTICS PVT. LTD.; RHIZEN PHARMACEUTICALS S.A.; MUTHUPPALANIAPPAN, Peyyappan; VISWANADHA, Srikant; MERIKAPUDI, Gayatri, Swaroop; VAKKALANKA, Swaroop, Kumar, V.S.
Patent: WO2011/42797 A1, 2011 ;
Location in patent: Page/Page column 69-70 ;
反应条件
hydrogenchloride in methanol; water 7 h; Heating;
参考文献
Bajnati, Abdelilah; Kokel, Bruno; Hubert-Habart, Michel
Bulletin de la Societe Chimique de France, 1987 , # 2 p. 318 - 324
