5-氨基-1-[5-(氟甲基)苯基]-1H-吡唑-4-羧酸乙酯合成路线 （共 3 条）
反应条件
in ethanol 24 h; RefluxInert atmosphere;
参考文献
GENENTECH, INC.; BLANEY, Jeffrey; GIBBONS, Paul A.; HANAN, Emily; LYSSIKATOS, Joseph P.; MAGNUSON, Steven R.; PASTOR, Richard; RAWSON, Thomas E.; ZHOU, Aihe; ZHU, Bing-Yan
Patent: WO2010/51549 A1, 2010 ;
Location in patent: Page/Page column 152 ;
WO 2010/051549 A1
反应条件
in ethanol 24 h; RefluxInert atmosphere;
参考文献
Genentech, Inc.
Patent: US2012/22043 A1, 2012 ;
Location in patent: Page/Page column 94-95 ;
US 20120022043 A1
反应条件
sodium acetate; acetic acid in water 16 h; heated on a steam bath;
参考文献
Beck, James R.; Gajewski, Robert P.; Lynch, Michael P.; Wright, Fred L.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 267 - 270
