N-(苯氧基乙酰基)-2'-脱氧腺苷合成路线 （共 7 条）
反应条件
1: 2-phenoxyacetic acid With pyridine; 4-nitro-phenol; dicyclohexyl-carbodiimide; TEA in 1,4-dioxane T=20°C; 2 h; 2: [14C]-2'-Deoxyadenosine With pyridine; dicyclohexyl-carbodiimide in 1,4-dioxane T=0°C; 2 h;
参考文献
Tripathi, Snehlata; Misra, Krishna; Sanghvi, Yogesh S.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 5045 - 5048
反应条件
1: pyridine / 0 deg C then warmed to r.t. for 1-2 h 2: 2.) EtOH, H2O / 1.) pyridine, acetonitrile, overnight, r.t.; 2.) 0 deg C View Scheme
参考文献
Schulhof, J. C.; Molko, D.; Teoule, R.
Tetrahedron Letters, 1987 , vol. 28, # 1 p. 51 - 54
反应条件
1: acetonitrile / Ambient temperature; 30-60 min 2: 2.) EtOH, H2O / 1.) pyridine, acetonitrile, overnight, r.t.; 2.) 0 deg C View Scheme
参考文献
Sinha; Sinha, Nanda D.; Davis; Davis, Peter; Schultze; Schultze, Lisa M.; Upadhya; Upadhya, Krishna
Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9277 - 9280
反应条件
sodium hydroxide 1.) pyridine, 3 h, room temperature, 2.) pyridine-EtOH, 10 min, 0 deg C; Yield given. Multistep reaction;
参考文献
Pirrung, Michael C.; Fallon, Lara; McGall, Glenn
Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 241 - 246
反应条件
pyridine; water; triethylamine
参考文献
Schulhof, J. C.; Molko, D.; Teoule, R.
Tetrahedron Letters, 1987 , vol. 28, # 1 p. 51 - 54
反应条件
ethanol; water 1.) pyridine, acetonitrile, overnight, r.t.; 2.) 0 deg C; Multistep reaction;
参考文献
Sinha; Sinha, Nanda D.; Davis; Davis, Peter; Schultze; Schultze, Lisa M.; Upadhya; Upadhya, Krishna
Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9277 - 9280
反应条件
sodium hydroxide in methanol; water 0.025 h; microwave irradiation;
参考文献
Nucleosides and Nucleotides, , vol. 17, # 9-11 p. 1761 - 1766
