hydrogenchloride in 1,4-dioxane 16 h; Ambient temperature;

1: N-methylmorpholine / toluene / 16 h / Ambient temperature 2: 64 percent / H2, AcOH / 5percent Pd/C / 5 h / 70 °C / 2280 Torr 3: 69 percent / diphenyl phosphorazidate, N-methylmorpholine / dimethylformamide / 16 h / Ambient temperature 4: 35 percent / 4 N aq. HCl / dioxane / 4 h / Ambient temperature 5: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 6: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 7: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 100 percent / p-toluenesulfonic acid*H2O / benzene / 5 h / Heating 2: 29 percent / H2 / 5percent Pd/C / propan-2-ol / 5 h / 50 °C / 2280 Torr 3: 86 percent / KOH / ethanol / 16 h / Ambient temperature 4: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 5: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 6: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 7: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 8: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 29 percent / H2 / 5percent Pd/C / propan-2-ol / 5 h / 50 °C / 2280 Torr 2: 86 percent / KOH / ethanol / 16 h / Ambient temperature 3: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 4: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 5: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 6: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 7: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 64 percent / H2, AcOH / 5percent Pd/C / 5 h / 70 °C / 2280 Torr 2: 69 percent / diphenyl phosphorazidate, N-methylmorpholine / dimethylformamide / 16 h / Ambient temperature 3: 35 percent / 4 N aq. HCl / dioxane / 4 h / Ambient temperature 4: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 5: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 6: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 86 percent / KOH / ethanol / 16 h / Ambient temperature 2: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 3: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 4: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 5: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 6: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 98 percent / conc. H2SO4 / 16 h / Ambient temperature 2: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 3: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 4: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 5: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 3: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 4: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 2: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 3: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme

1: 35 percent / 4 N aq. HCl / dioxane / 4 h / Ambient temperature 2: 80 percent / Et3N / CH2Cl2 / 16 h / Ambient temperature 3: 94 percent / NaH / dimethylformamide / 5 h / Ambient temperature 4: 78 percent / 4 N aq. HCl / dioxane / 16 h / Ambient temperature View Scheme