N2-乙酰基-9-[(2-羟基乙氧基)甲基]胍合成路线 （共 7 条）
反应条件
sodium methylate in methanol T=23°C; 0.266667 h;
参考文献
Gao; Mitra
Synthetic Communications, 2001 , vol. 31, # 9 p. 1399 - 1419
反应条件
4-(N,N-dimethlyamino)pyridine 120 h; Ambient temperature;
参考文献
Martin; McGee; Jeffrey; Hobbs; Smee; Matthews; Verheyden
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1384 - 1389
反应条件
palladium diacetate; triethylammonium formate; triphenylphosphine in 1,4-dioxane T=90°C; 1 h; Further byproducts given;
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 625 - 636
反应条件
1: 75 percent / pyridine / 1 h / Heating 2: 67 percent / NaOMe / methanol / 0.27 h / 23 °C View Scheme
参考文献
Synthetic Communications, , vol. 31, # 9 p. 1399 - 1419
反应条件
1.1: triflic acid / 32 h / 160 °C 1.2: 93 percent / 12 h / Heating 2.1: 85 percent / acetic acid / H2O / 2 h / 80 °C 3.1: 75 percent / pyridine / 1 h / Heating 4.1: 67 percent / NaOMe / methanol / 0.27 h / 23 °C View Scheme
参考文献
Synthetic Communications, , vol. 31, # 9 p. 1399 - 1419
反应条件
1: 85 percent / acetic acid / H2O / 2 h / 80 °C 2: 75 percent / pyridine / 1 h / Heating 3: 67 percent / NaOMe / methanol / 0.27 h / 23 °C View Scheme
参考文献
Synthetic Communications, , vol. 31, # 9 p. 1399 - 1419
反应条件
hydrogen; palladium on activated charcoal in ethanol T=70°C; 1 h; other reagents; Product distribution;
参考文献
Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 625 - 636
