(Z)-3-甲氧基-6-(3,4,5-三甲氧基苯乙烯)苯-1,2-二醇合成路线 （共 14 条）
反应条件
1: With bis(cyclohexanyl)borane in tetrahydrofuran T=0°C; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
Tetrahedron Letters, , vol. 47, # 7 p. 1101 - 1103
反应条件
potassium fluoride; hydrogen bromide in N,N-dimethyl-formamide 2 h; Sonication;
参考文献
Journal of Natural Products, , vol. 72, # 3 p. 414 - 421
反应条件
titanium tetrachloride in dichloromethane T=0°C; 0.666667 h;
参考文献
Journal of Natural Products, , vol. 72, # 3 p. 414 - 421
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Tetrahedron Letters, , vol. 43, # 15 p. 2839 - 2841
反应条件
1.1: 83 percent / DIPEA / CH2Cl2 2.1: 98 percent / n-BuLi; I2 / tetrahydrofuran / -78 °C 3.1: 85 percent / n-PrNH2; CuI / Pd(PPh3)4 / Heating 4.1: BH(C6H11)2 / tetrahydrofuran / 0 °C 4.2: 74 percent / HCl / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 7 p. 1101 - 1103
反应条件
1.1: 98 percent / n-BuLi; I2 / tetrahydrofuran / -78 °C 2.1: 85 percent / n-PrNH2; CuI / Pd(PPh3)4 / Heating 3.1: BH(C6H11)2 / tetrahydrofuran / 0 °C 3.2: 74 percent / HCl / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 7 p. 1101 - 1103
反应条件
1.1: 85 percent / n-PrNH2; CuI / Pd(PPh3)4 / Heating 2.1: BH(C6H11)2 / tetrahydrofuran / 0 °C 2.2: 74 percent / HCl / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 7 p. 1101 - 1103
反应条件
1.1: MgCl2; Et3N; CH2O / tetrahydrofuran / Heating 1.2: 55 percent / NaOH; H2O2 / H2O 2.1: 83 percent / DIPEA / CH2Cl2 3.1: 98 percent / n-BuLi; I2 / tetrahydrofuran / -78 °C 4.1: 85 percent / n-PrNH2; CuI / Pd(PPh3)4 / Heating 5.1: BH(C6H11)2 / tetrahydrofuran / 0 °C 5.2: 74 percent / HCl / tetrahydrofuran; H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 7 p. 1101 - 1103
反应条件
1.1: 5 g / E. coli JM109 (pDTG602); fermentation broth / 2 h / fermentation 2.1: 90 percent / EtN(i-Pr)2 / CH2Cl2 3.1: n-BuLi; B(Oi-Pr)3 / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C 3.2: Pd(PPh3)4 / 90 °C / Suzuki-Miyaura coupling 4.1: (C6H11)2BH / 0 - 20 °C 4.2: 84 percent / HOAC / 4 h / 0 °C 5.1: 77 percent / HCl / tetrahydrofuran View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 15 p. 2839 - 2841
反应条件
1.1: n-BuLi; B(Oi-Pr)3 / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C 1.2: Pd(PPh3)4 / 90 °C / Suzuki-Miyaura coupling 2.1: (C6H11)2BH / 0 - 20 °C 2.2: 84 percent / HOAC / 4 h / 0 °C 3.1: 77 percent / HCl / tetrahydrofuran View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 15 p. 2839 - 2841
