2-羟甲基-1,4-苯并二噁烷对甲苯磺酸酯合成路线 （共 7 条）
反应条件
1: NaN3 2: H2 / Pd/C View Scheme
参考文献
Xian, Ming; Li, Xiaopeng; Tang, Xiaoping; Chen, Xinchao; Zheng, Zhongling; Galligan, James J; Kreulen, David L; Wang, Peng G
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2377 - 2380
反应条件
T=140°C; Alkylation; 20 h;
参考文献
Mayer; Brunel; Chaplain; Piedecoq; Calmel; Schambel; Chopin; Wurch; Pauwels; Marien; Vidaluc; Imbert
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3653 - 3664
反应条件
1: NaN3 2: H2 / Pd/C 3: Et3N 4: SnCl4 View Scheme
参考文献
Xian, Ming; Li, Xiaopeng; Tang, Xiaoping; Chen, Xinchao; Zheng, Zhongling; Galligan, James J; Kreulen, David L; Wang, Peng G
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2377 - 2380
反应条件
triethylamine; di(n-butyl)tin oxide in dichloromethane
T=20°C; 6 h;
参考文献
Martinelli, Michael J.; Vaidyanathan, Rajappa; Pawlak, Joseph M.; Nayyar, Naresh K.; Dhokte, Ulhas P.; Doecke, Christopher W.; Zollars, Lisa M. H.; Moher, Eric D.; Khau, Vien Van; Kosmrlj, Berta
Journal of the American Chemical Society, 2002 , vol. 124, # 14 p. 3578 - 3585
反应条件
1: titanium tetrachloride; sodium tetrahydroborate / ethylene glycol dimethyl ether / 0 - 20 °C
2: pyridine / 0 - 20 °C
View Scheme
参考文献
Liu, Xin; Wang, Songlin; Chen, Yin; Liu, Xinghua; Xu, Xiangqing; Liu, Bi-Feng; Zhang, Guisen
Archiv der Pharmazie, 2014 , vol. 347, # 1 p. 32 - 41
参考文献
Liu, Xin; Wang, Songlin; Chen, Yin; Liu, Xinghua; Xu, Xiangqing; Liu, Bi-Feng; Zhang, Guisen
Archiv der Pharmazie, 2014 , vol. 347, # 1 p. 32 - 41
反应条件
T=120°C; Alkylation; 16 h;
参考文献
Mayer; Brunel; Chaplain; Piedecoq; Calmel; Schambel; Chopin; Wurch; Pauwels; Marien; Vidaluc; Imbert
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3653 - 3664
