3-(2-甲氧基-5-甲基苯基)-3-苯基丙酸合成路线 （共 9 条）
反应条件
1: 3,4-dihydro-6-methyl-4-phenyl-2H-benzopyran-2-one With water; sodium hydroxide T=60 - 65°C; 2 h; 2: dimethyl sulfate in water T=20°C; 3 h;
参考文献
ALEMBIC LIMITED; PONNAIAH, Ravi; DESAI, Sanjay; SHAH, Chankrakant Chunilal; PATEL, Kalpesh Shantibhai; PAREKH, Viral Maheshbhai
Patent: WO2010/92500 A2, 2010 ;
Location in patent: Paragraph 148-155 ;
反应条件
1: With bis(cyclohexanyl)borane in tetrahydrofuran T=0°C; 1.5 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; methanol; water
参考文献
Organic Letters, , vol. 6, # 8 p. 1325 - 1327
反应条件
1.1: 90 percent / potassium hexafluorophosphate / (dppm)Re(O)Cl3 / nitromethane / Heating 2.1: dicyclohexylborane / tetrahydrofuran / 1.5 h / 0 °C 2.2: sodium hydroxide; hydrogen peroxide / tetrahydrofuran; methanol; H2O View Scheme
参考文献
Organic Letters, , vol. 6, # 8 p. 1325 - 1327
反应条件
1.1: 90 percent / potassium hexafluorophosphate / (dppm)Re(O)Cl3 / nitromethane / Heating 2.1: dicyclohexylborane / tetrahydrofuran / 1.5 h / 0 °C 2.2: sodium hydroxide; hydrogen peroxide / tetrahydrofuran; methanol; H2O View Scheme
参考文献
Organic Letters, , vol. 6, # 8 p. 1325 - 1327
反应条件
1.1: 90 percent / potassium hexafluorophosphate / (dppm)Re(O)Cl3 / nitromethane / Heating 2.1: dicyclohexylborane / tetrahydrofuran / 1.5 h / 0 °C 2.2: sodium hydroxide; hydrogen peroxide / tetrahydrofuran; methanol; H2O View Scheme
参考文献
Organic Letters, , vol. 6, # 8 p. 1325 - 1327
反应条件
toluene-4-sulfonic acid T=125°C; 3 h;
参考文献
Tetrahedron Letters, , vol. 48, # 28 p. 4895 - 4898
反应条件
1: hydrogen fluoride / 100 °C View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 587, p. 1,15
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran T=20°C; 2: With methanesulfonic acid in tetrahydrofuran T=20 - 70°C; Product distribution / selectivity;
参考文献
ALEMBIC LIMITED; PONNAIAH, Ravi; DESAI, Sanjay; SHAH, Chankrakant Chunilal; PATEL, Kalpesh Shantibhai; PAREKH, Viral Maheshbhai
Patent: WO2010/46801 A2, 2010 ;
Location in patent: Page/Page column 16 ;
反应条件
thionyl chloride; diisopropylamine in dichloromethane; water
参考文献
US5382600 A1, ;
US 5382600 A
