1: H2 / 10percent Pd/C / ethyl acetate; methanol / Ambient temperature 2: Et3N / CH2Cl2 / 6 h / Ambient temperature 3: 89 percent / 1 M LiOH / ethanol / 2 h 4: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride (EDCI) / dimethylformamide / 12 h / Ambient temperature 5: HCl(g) / 2 h / 0 - 20 °C 6: ammonia / ethanol / 8 h / Ambient temperature 7: H2 / 10percent Pd/C / methanol / 4 h / 2280 Torr / Ambient temperature 8: formic acid / 12 h / Ambient temperature View Scheme