1-乙酰基-5-氯-1H-吲哚-3-基乙酸酯合成路线 （共 5 条）
反应条件
1: With sodium acetate T=60°C; 5 h; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
Cheng, Jingcai
Patent: US2010/137356 A1, 2010 ;
Location in patent: Page/Page column 9 ;
反应条件
1: chloroacetic acid; 2-amino-5-chloro-benzoic acid With sodium hydroxide in water Heating; 2: acetic anhydride With sodium acetate in water; N,N-dimethyl-formamide Heating;
参考文献
Nirogi, Ramakrishna V.S.; Deshpande, Amol D.; Kambhampati, Ramasastri; Badange, Rajesh Kumar; Kota, Laxman; Daulatabad, Anand V.; Shinde, Anil K.; Ahmad, Ishtiyaque; Kandikere, Vishwottam; Jayarajan, Pradeep; Dubey
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 346 - 349
反应条件
1: sodium hydroxide / water 2: sodium acetate / N,N-dimethyl-formamide / 120 °C View Scheme
参考文献
Nirogia, Ramakrishna V.S.; Kambhampati, Ramasastri; Daulatabad, Anand V.; Gudla, Parandhama; Shaikh, Mohammad; Achanta, Pramod Kumar; Shinde, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2011 , vol. 26, # 3 p. 341 - 349
反应条件
sodium hydroxide; water unter Stickstoff und Behandeln der Reaktionsloesung mit Acetanhydrid;
参考文献
Holt; Sadler
Pr.roy.Soc.<B>, 1958 , vol. 148, p. 481,491,493
反应条件
sodium sulfite in ethanol
Heating;
参考文献
Nirogia, Ramakrishna V.S.; Kambhampati, Ramasastri; Daulatabad, Anand V.; Gudla, Parandhama; Shaikh, Mohammad; Achanta, Pramod Kumar; Shinde, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2011 , vol. 26, # 3 p. 341 - 349
