3-(4-氯苯基)-1-苯基吡唑-4-丙酸合成路线 （共 5 条）
反应条件
hydrogen; platinum(IV) oxide in tetrahydrofuran 7 h; Ambient temperature;
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: 83 percent / pyridine; piperidine / 4 h / Heating 2: 58 percent / NaOH; hydrazine hydrate / Renay nickel / ethanol / Heating View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
triethylamine-formic acid T=95 - 100°C; 2 h;
参考文献
Jagath Reddy; Srinivasa Rao; Khalilullah; Thirupathaiah; Latha
Heterocyclic Communications, 2006 , vol. 12, # 6 p. 423 - 426
反应条件
1: 89.6 percent / POCl3 2: 80 percent / piperidine 3: 76.6 percent / NaOH / methanol; H2O / 2 h / Heating 4: pyridine / 0.5 h / 100 °C 5: 74.9 percent / H2 / PtO2 / tetrahydrofuran / 7 h / Ambient temperature View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: pyridine / 0.5 h / 100 °C 2: 74.9 percent / H2 / PtO2 / tetrahydrofuran / 7 h / Ambient temperature View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
