1,3-二苯基吡唑-4-丙酸合成路线 （共 6 条）
反应条件
hydrogen; platinum(IV) oxide in tetrahydrofuran 7 h; Ambient temperature;
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: 78 percent / pyridine; piperidine / 4 h / Heating 2: 64 percent / NaOH; hydrazine hydrate / Renay nickel / ethanol / Heating View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
1: 71.3 percent / POCl3 2: 93.8 percent / piperidine / pyridine / 95 - 100 °C 3: 88.2 percent / H2 / PtO2 / tetrahydrofuran / 7 h / Ambient temperature View Scheme
参考文献
Bernard; Hulley; Molenda; Stochla; Wrzeciono
Die Pharmazie, 1986 , vol. 41, # 8 p. 560 - 562
反应条件
triethylamine-formic acid T=95 - 100°C; 2 h;
参考文献
Jagath Reddy; Srinivasa Rao; Khalilullah; Thirupathaiah; Latha
Heterocyclic Communications, 2006 , vol. 12, # 6 p. 423 - 426
反应条件
1: methanol / Reflux 2: trichlorophosphate / 70 °C / Cooling with ice 3: piperidine / pyridine / 95 - 100 °C 4: Pearlman's catalyst; ammonium formate / ethyl acetate View Scheme
参考文献
Deepa; Harinadha Babu; Madhava Reddy
Indian Journal of Heterocyclic Chemistry, 2011 , vol. 20, # 3 p. 213 - 216
反应条件
1: methanol / Reflux 2: trichlorophosphate / 70 °C / Cooling with ice 3: piperidine / pyridine / 95 - 100 °C 4: Pearlman's catalyst; ammonium formate / ethyl acetate View Scheme
参考文献
Deepa; Harinadha Babu; Madhava Reddy
Indian Journal of Heterocyclic Chemistry, 2011 , vol. 20, # 3 p. 213 - 216
