反应条件
1: 1.) BuLi / 1.) THF, hexane, -70 deg C, 30 min, 2.) -65 deg C, 2 h 2: H2 / 5percent Rh/Al2O3 / ethanol; aq. NH3 3: 1.) NaHCO3, 2.) LiAlH4 / 1.) CH2Cl2, RT, 20 h, 2.) THF, reflux, 1.5 h View Scheme
参考文献
Yardley; Morris Husbands; Stack; Butch; Bicksler; Moyer; Muth; Andree; Fletcher III; James; Sielecki
Journal of Medicinal Chemistry, 1990 , vol. 33, # 10 p. 2899 - 2905
