反应条件
1: 1.) Mg / 1.) ether, 0-5 deg C; 2.) 4 h, r.t., ether
2: 71 percent / 1.) 50 percent NaH / 1.) DMSO, oil, r.t., 30 min.; 2.) DMSO, THF, r.t., 4 h
3: 73 percent / 70 percent t-butylhydroperoxide, Et4NOAc*4H2O / OsO4 / acetone
4: 94 percent / p-TsOH / benzene / 1 h / Heating
5: imidazole / dimethylformamide / 6 h / Ambient temperature
6: 1.) 50 percent NaH, ethyl oxalate; 2.) K2CO3 / 1.) oil, THF, EtOH, 4 h, r.t.; 2.) oil, THF, H2O, 1.5 h, 0 deg C
7: 79.8 percent / acetic acid; tetrahydrofuran; H2O / 72 h / Ambient temperature
View Scheme
参考文献
Machiya; Ichimoto; Tonari; et al.
Agricultural and Biological Chemistry, 1985 , vol. 49, # 6 p. 1767 - 1773
