吲哚-6-羧酸乙酯-2-羧酸乙酯合成路线 (共 7 条)
反应条件
acetic acid; zinc T=75°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 3 p. 938 - 941
参考文献
Journal of the American Chemical Society, , vol. 79, p. 1745,1747
反应条件
1: aqueous NaOH 2: etheric diazoethane solution View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 1745,1747
反应条件
1: aqueous methanol. KOH 2: aqueous NaOH 3: etheric diazoethane solution View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 1745,1747
反应条件
1.1: sodium ethanolate / ethanol / 16 h / 20 °C 1.2: pH 7 2.1: zinc; acetic acid / water / 1 h / 85 °C View Scheme
参考文献
WO2011/71716 A1, ;
WO 2011/071716 A1
反应条件
1.1: hydrogenchloride / 20 h / 90 °C / Inert atmosphere 2.1: sodium ethanolate / ethanol / 16 h / 20 °C 2.2: pH 7 3.1: zinc; acetic acid / water / 1 h / 85 °C View Scheme
参考文献
WO2011/71716 A1, ;
WO 2011/071716 A1
参考文献
Kermack
Journal of the Chemical Society, 1924 , vol. 125, p. 2288