4-氯-3-甲基-1-氧吡啶合成路线 （共 6 条）
反应条件
1: 2 h; Heating / refluxNeat (no solvent); 2: With sodium carbonate in water T=0°C;
参考文献
WO2008/63625 A2, ;
Page/Page column 134 ;
WO 2008/063625 A2
反应条件
hydrogenchloride; triethylbutylammonium chloride in water; acetonitrile T=65°C; 10 h;
参考文献
Russian Journal of Organic Chemistry, , vol. 44, # 12 p. 1824 - 1830
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
参考文献
US2004/14759 A1, ;
Page/Page column 12 ;
反应条件
1: concentrated sulfuric acid; nitric acid / 105 °C View Scheme
参考文献
Yakugaku Zasshi, , vol. 75, p. 292,294
Chem.Abstr., , p. 1808
反应条件
sodium hydrogensulfide in ethanol
168 h; Heating / reflux;
参考文献
ADOLOR CORPORATION
Patent: WO2008/63625 A2, 2008 ;
Location in patent: Page/Page column 135 ;
WO 2008/063625 A2
参考文献
Katritzky
Journal of the Chemical Society, 1956 , p. 2404,2407
