2,6-二甲基吡啶 N-氧化物合成路线 （共 36 条）
反应条件
dihydrogen peroxide; Na12[WZn3(H2O)2(ZnW9O34)2] T=75°C; 7 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 346, # 2-3 p. 339 - 345
反应条件
in acetonitrile MeN4Cl adding to the polarographic test soln. prepared from SnCl4*5H2O in acetonitrile containing a ligand in a molar ratio 2:1 and 1 M Pr4NClO4 as a supporting electrolyte under N2; detected polarographically;
参考文献
Polyhedron, , vol. 2, p. 479 - 484
反应条件
in acetonitrile T=24.84°C; Equilibrium constant;
参考文献
Russian Journal of General Chemistry, , vol. 78, # 6 p. 1241 - 1246
反应条件
1: 2,6-dimethylpyridine N-oxide With dimethyl sulfate 1 h; 2: potassium cyanide in water 48 h;
参考文献
DOV PHARMACEUTICAL, INC.
Patent: WO2005/84439 A1, 2005 ;
Location in patent: Page/Page column 31 ;
WO 2005/084439 A1
反应条件
methyl iodide Behandeln des Reaktionsprodukts mit KCN in wss. Dioxan;
参考文献
Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 925,928
Full Text Show Details
Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 130,925, 929
反应条件
1: 86 percent / 2 h / 80 °C 2: 18 percent / H2O / 24 h / 20 °C View Scheme
参考文献
Charier, Sandrine; Ruel, Odile; Baudin, Jean-Bernard; Alcor, Damien; Allemand, Jean-Francois; Meglio, Adrien; Jullien, Ludovic; Valeur, Bernard
Chemistry - A European Journal, 2006 , vol. 12, # 4 p. 1097 - 1113
反应条件
1: With hydrogenchloride in water T=10 - 20°C; 2: With trichlorophosphate 8 h; Reflux; 3: With potassium carbonate in water T=0°C;
参考文献
EVOTEC NEUROSCIENCES GMBH
Patent: WO2009/135842 A1, 2009 ;
Location in patent: Page/Page column 81 ;
WO 2009/135842 A1
反应条件
1: 86 percent / 2 h / 80 °C 2: 18 percent / H2O / 24 h / 20 °C 3: 78 percent / KOH / ethanol / 3 h / Heating View Scheme
参考文献
Charier, Sandrine; Ruel, Odile; Baudin, Jean-Bernard; Alcor, Damien; Allemand, Jean-Francois; Meglio, Adrien; Jullien, Ludovic; Valeur, Bernard
Chemistry - A European Journal, 2006 , vol. 12, # 4 p. 1097 - 1113
反应条件
1: 84 percent / H2SO4, HNO3 / 3 h / 125 - 130 °C 2: 97 percent / H2, gl. AcOH / 10percent Pd/C / 19 h / 50 °C / 2327.2 Torr View Scheme
参考文献
Tanga; Bupp; Tochimoto
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 717 - 727
反应条件
methyl iodide Behandeln des Reaktionsprodukts mit KCN in wss. Dioxan;
参考文献
Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 925,928
Full Text Show Details
Okamoto; Tani
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 130,925, 929
